As knowledge was growing, Zadig has published and updated a course on the pharmaceutical therapies being used to treat COVID-19, which in the early phase of the pandemic were the only option while waiting for vaccines. For each medication, a fact sheet explains the rationale for use, trials conducted or in progress, dosages, evidence of efficacy and safety profile. The course not only provides contents for clinical practice, but also includes the most relevant literature references to deepen the topic.

First in Italy, Zadig has published an e-learning course on the home management of patients with COVID-19, which is fundamental not only for the individual patient but also to prevent hospitals from having too many inappropriate admissions, especially during an epidemic wave.

For the year 2021, in partnership with the Lazzaro Spallanzani National Institute for Infectious Diseases, Zadig offers on the SAEPE technological platform an e-learning course that provides evidece-based and continuosly updated information on SARS-CoV-2 and COVID-19 and an e-learning course on SARS-CoV-2 vaccines that is updated in parallel with the approval of the different vaccines.

Zadig has developed and published an online course focused on the use of personal protective equipment (PPE) and the dressing and undressing procedures (donning and doffing) for healthcare workers involved in the new coronavirus emergency. The course is provided vie the SAEPE technological platform and is open to all healthcare professionals.

Zadig has developed an online course on pregnancy, childbirth and breastfeeding in the days of COVID-19. It provides practical guidance on how preventing the infection and managing these crucial moments in a woman's life, as well as regular updates on still open issues.

As soon as the clinical experience gathered in the few months since the pandemic began has shown the sequelae of COVID-19, with disabling symptoms persisting weeks or months later, Zadig has developed a course on the syndrome named "long COVID".

Zadig has developed and published an online course on smart working. This new way of working, increasingly widespread because of the pandemics, must be carried out safely, meaning that companies must act properly and be concerned about the health of remote workers. The course delivered on the SAEPE platform is open to all healthcare workers.

Based on the regulations from the Italian Ministry of Health, Zadig has developed and published a course on workers' safety in times of pandemic. The knowledge of these guidance documents is essential to minimise the risk of contagion in the workplace.

The second module of the educational project Novel Learning that aims to merge the two most important branches of the modern medicine, namely evidence based medicine and narrative medicine, is focused on the prevention and management of pressure ulcers, a high priority topic during the SARS-CoV-2 pandemic since numerous healthcare workers experienced facial skin injuries or pressure ulcers due to the prolonged use of personal protective equipment (PPI).

Zadig has created a section on the pandemic emergency on the website of the National Centre for Screening Monitoring (ONS), following the changes in the screening programs in the different Italian regions and beginning a debate on the future of these oncological prevention programs once the pandemic has ended.

Also for the website of the National Centre for Disease Prevention and Control (Centro per il Controllo delle Malattie, CCM) of the Ministry of Health, the editorial staff of Zadig regularly updates the pages dedicated to the COVID-19 emergency.

Zadig was the editor of the special issue of Humanitas Magazine dealing with COVID-19, managing the graphical design and the editorial process. .